1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity associated with bortezomib, a proteasome inhibitor used in the remedy of multiple myeloma. Its synthesis or examine is critical for making certain the purity and safety of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor while in the synthesis of abiraterone acetate, a drug used in the procedure of prostate most cancers by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-ten-one): A critical compound inside the synthesis of imatinib, a drug that targets specific sorts of cancer, such as Serious myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Utilized in the synthesis of docetaxel, a chemotherapy medication that treats various cancers for example breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates inside the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the 5 generation procedure and guaranteeing high purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is used to deal with breast cancer, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist used in the treatment method of breast most cancers. Many intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-nine): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug effective in treating cancers for example ovarian, breast, and lung most cancers.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the remedy of colorectal cancer and small cell lung 4S)-3-Hydroxy-4-phenyl-2-azetidinone cancer.
three-Amino-one-hydroxyadamantane (CAS 702-82-nine): This compound is involved in the synthesis of adamantane derivatives, which have several purposes, such as antiviral Homes.
Vildagliptin Intermediates: Utilized in the manufacture of vildagliptin, an oral drug for variety two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of varied gluconic acid derivatives, which might be Employed in foods, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication employed to handle kind two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).